Chiasma is focused on improving the lives of patients who face challenges associated with their existing treatments for rare and serious chronic diseases. Employing its Transient Permeability Enhancer (TPE®) technology platform, Chiasma seeks to develop oral medications that are currently available only as injections. In July 2019, the Company reported positive top-line data from its completed Phase 3 clinical trial of its octreotide capsules product candidate, conditionally trade named MYCAPSSA, for the maintenance therapy of adult patients with acromegaly. In January 2020, the FDA accepted for review the resubmission of Chiasma’s New Drug Application seeking marketing approval for MYCAPSSA in the United States and assigned PDUFA action date of June 26, 2020. The Company is also currently conducting a Phase 3 multinational clinical study designed for EMA commercial approval.  Chiasma is headquartered in Needham, MA with a wholly owned Israeli subsidiary. 

The Manager, Medical Information (MI) is responsible for providing drug and disease state information to physicians and other healthcare providers, patients, and Chiasma personnel.  Likewise, the Manager will personify the well-respected, well-informed credible professional who is the clinical/scientific/technical face for Chiasma. Career ladder plan for this position will be to take over all aspects of MI for Chiasma, including but not limited to vendor and outsourced call center management. 


  • Proactively develop and maintain a comprehensive and medically accurate database for Chiasma products

  • Utilize clinical expertise to provide medical information to Healthcare Professionals through responding to medical inquiries

  • Develop relevant, reliable, appropriate, and balanced responses to queries

  • Develop responses in anticipation of trends in medicine as they relate to Chiasma products

  • Respond to emergency inquiries during non-business hours from Healthcare Professionals escalated by Chiasma after-hours provider (Estimated to be < 5 times/year)

  • Document the inquiry and response process

  • Perform Medical review for promotional and medical review committees

  • Review internal/external literature

  • Critically evaluate the published medical and scientific literature related to Chiasma and its products or areas of interest

  • Recognize and perform Adverse Event and Product Complaint referrals

  • Provide in-house product and disease state technical training for Chiasma in-house, MI vendors, and field personnel

  • Support product specific medical information at Chiasma exhibits during national meetings 

  • Train/Precept post-doctoral Pharm.D. fellows or MI interns (if applicable)

  • Update and maintain procedural documents


  • Advanced health care professional degree (Pharm.D.) and 2-3 years of experience in Medical Information (MI) services at a pharmaceutical or biotech company 

  • Experience in Medical review on Promotional Review Committees (2-3 years)

  • 3-5+ years of experience in Medical Information (MI) services at a pharmaceutical or biotech company (Preferred)

  • Previous experience with Information Request Management System (IRMS), Veeva Vault and/or similar MI database software (Preferred)

  • Rare disease or orphan drug experience a strong plus (Preferred)

  • Vendor management experience (Preferred)

  • Effective Communication 

  • Customer Focused

  • Enterprise Perspective

  • Team player

  • Decisiveness

  • Professional Confidence

Chiasma Inc. (the "Company") is an equal opportunity employer.  All qualified applicants will be considered without regard to age, race, color, sex, religion/creed, national origin, marital status, ancestry, citizenship, military, reservist or veteran status, pregnancy, sexual orientation or preference, gender identity, gender expression, physical or mental disability, genetic predisposition or carrier status, or any other category protected under applicable federal, state or local law.  Consistent with its obligations under applicable law, the Company will make reasonable accommodations for qualified individuals with disabilities.  If you require an accommodation in the application process, please contact a member of the Company’s Human Resources department.