Chiasma is a late stage Phase 3 biopharmaceutical company focused on improving the lives of patients suffering from orphan diseases by developing and commercializing novel oral forms of therapies that are available today only by injection. The company’s lead product candidate is octreotide capsules for the orphan condition acromegaly and is currently in Phase 3 multinational clinical studies designed for both FDA and EMA commercial approval. Chiasma is a well-funded, public Delaware corporation (Nasdaq: CHMA) with wholly owned Israeli subsidiary.

The Director, Infrastructure and Operations will lead the delivery of infrastructure and end-user support services to the company. The Director will work with both internal and external resources to establish and maintain a “what great looks like” service model for the delivery of core IT services. The Director will set the standards that the service delivery model will be measured by and ensure that those standards are met. In addition, the Director will work closely with the business to ensure that the core IT services meet the needs of the business and are effectively being used. The Director Infrastructure and Operations will report to the Vice President, Information Technology.


  • Ownership of the IT infrastructure and operations, which includes the network, servers, back office applications (Office 365, Okta, Mimecast, etc.), supporting services, training services, and end-user support
  • Deliver effective service management through the definition and adoption of a governance practice that uses KPIs and other metrics to measure the quality of service and that fosters continuous service improvement
  • Ensure that the services provide meet the needs of the company, are effectively being used by hosting periodic training sessions, and are cost effective for the company
  • Recommend strategic direction, standards, methodologies, tools, priorities, and approaches for the infrastructure architecture
  • Establish and maintain a positive relationship with internal business partners and strategic service partners to effectively manage the changing needs of the business
  • Stay abreast of current and emerging technologies and best practices, and how other organizations are utilizing them
  • Develop statements of work, contracts, managed service and service level agreements as related to the implementation and management of the application portfolio
  • Train and disseminate application implementation, development, and management standards, guidelines, and directions throughout the organization
  • Lead application implementation, development, and configuration through a structured methodology to successfully deliver new systems and changes to existing systems


  • A forward-looking, run to the work, solution seeking mindset
  • At least 8 years of technical experience with demonstrated success as a leader
  • Bachelor’s degree or equivalent required
  • Previous experience in the pharmaceutical industry is a must
  • Proven experience in leading transformational initiatives in a dynamic environment
  • Excellent communication and influencing skills, with demonstrated ability to work collaboratively with partners internal and external to the company
  • Strong vendor management and partner relation skills to ensure that the quality of the service (application or support) provided meets the needs of the company and the contractual obligations
  • Strong analytical, conceptual thinking, strategic planning, and execution skills
  • Ability to link work priorities to business imperatives
  • Application of appropriate regulatory and statutory compliance, including GxP, SOX, GDPR, and information security
  • Prior experience in budgeting and tracking, roadmap development, status reporting, etc.
  • Team leader with the ability to set specific measurable milestones and the progress monitoring of them
  • Experience in hiring, managing, and developing a technical team that is both internal and outsourced
  • Strong management skills and the ability to operate both strategically and tactically (hands-on)

Chiasma Inc. (the "Company") is an equal opportunity employer. All qualified applicants will be considered without regard to age, race, color, sex, religion/creed, national origin, marital status, ancestry, citizenship, military, reservist or veteran status, pregnancy, sexual orientation or preference, gender identity, gender expression, physical or mental disability, genetic predisposition or carrier status, or any other category protected under applicable federal, state or local law. Consistent with its obligations under applicable law, the Company will make reasonable accommodations for qualified individuals with disabilities. If you require an accommodation in the application process, please contact a member